Endocrine Abstracts

We report a case of acute adrenal crisis in a patient with the antiphospholipid syndrome in a man who was on a therapeutic dose of warfarin. A 64-year-old man presented with vomiting and abdominal discomfort. Temperature was 37.8 °C, pulse 85/min and BP 100/63 mmHg. On examination, there was generalized hyperpigmentation. He had a history of deep venous thrombosis of the lower limbs on two occasions and was on warfarin. He previously diagnosed primary antiphospho...

Introduction: Anti-phospholipid syndrome is characterised by the presence of arterial or venous thrombosis, it is autoimmune in nature and manifests as a systemic disease. Adrenal vein haemorrhagic infarction which is a sequel of adrenal vein thrombosis ultimately leads to loss of adrenal function, it is one of the presentations of anti-phospholipid syndrome especially with catastrophic type. In one analysis adrenal involvement was reported in only 13% of the reported cases of...